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人体肝脏中铜、锰和锌的测定。

Determination of copper, manganese and zinc in human liver.

作者信息

Treble R G, Thompson T S, Lynch H R

机构信息

Saskatchewan Health, Provincial Laboratory, Environmental Toxicology Section, Regina, Canada.

出版信息

Biometals. 1998 Jan;11(1):49-53. doi: 10.1023/a:1009209408034.

DOI:10.1023/a:1009209408034
PMID:9450317
Abstract

Autopsied liver tissue samples collected from 42 males and 31 females were analyzed for copper, manganese and zinc using atomic absorption spectrometry (AAS). With the exception of two liver samples for which the copper levels were determined to be 74.8 and 104.0 micrograms/g (dry weight), hepatic copper concentrations were found to range from 1.7 to 32.4 micrograms/g with a mean concentration of 14.2 micrograms/g and standard deviation of 7.0 micrograms/g. Manganese concentrations (with the exception of one sample having 12.9 micrograms/g) ranged from 0.22 to 4.6 micrograms/g with a mean of 2.26 +/- 1.00 micrograms/g. Hepatic zinc levels averaged 118.3 +/- 44.4 micrograms/g and ranged from 38.5 to 231.3 micrograms/g. There were no apparent trends for the levels of any metals versus age nor were there any differences in average hepatic metal concentrations for males and females.

摘要

使用原子吸收光谱法(AAS)对从42名男性和31名女性身上采集的肝脏组织样本进行了铜、锰和锌含量分析。除了两个肝脏样本的铜含量分别测定为74.8和104.0微克/克(干重)外,肝脏铜浓度范围为1.7至32.4微克/克,平均浓度为14.2微克/克,标准差为7.0微克/克。锰浓度(除了一个样本为12.9微克/克)范围为0.22至4.6微克/克,平均值为2.26±1.00微克/克。肝脏锌水平平均为118.3±44.4微克/克,范围为38.5至231.3微克/克。任何金属含量与年龄之间均无明显趋势,男性和女性的平均肝脏金属浓度也没有差异。

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