Schläpfer J, Yang Y, Rexroad C, Womack J E
Institute of Animal Breeding, University of Berne, Switzerland.
Chromosome Res. 1997 Dec;5(8):511-9. doi: 10.1023/a:1018485401403.
In this paper we present a 5000-rad radiation hybrid framework map of bovine chromosome 13 (BTA13) containing 13 loci, including five conserved genes and eight polymorphic microsatellites. All framework markers are ordered with odds greater than 1000:1. Furthermore, we present a comprehensive map of BTA13 integrating 11 genes and 16 microsatellites. The proposed order is in general agreement with the recently published medium-density linkage maps. A model of five blocks of genes with conserved order between human, mouse and cattle is presented.
在本文中,我们展示了一张牛13号染色体(BTA13)的5000拉德辐射杂种框架图,其中包含13个位点,包括5个保守基因和8个多态性微卫星。所有框架标记的排序优势比均大于1000:1。此外,我们还展示了一张整合了11个基因和16个微卫星的BTA13综合图谱。所提出的顺序总体上与最近发表的中密度连锁图谱一致。我们提出了一个人类、小鼠和牛之间基因顺序保守的五个基因块模型。