Ngan J, Kind S L
Int Arch Allergy Appl Immunol. 1976;51(3):311-9. doi: 10.1159/000231605.
Neonatal SWR mice are capable of synthesizing reagins when immunized with a mixture of concanavalin and ovalbumin or a mixture of Bordetella pertussis, alum and ovalbumin. Reaginic antibody-forming cells can be found in the spleen, lymph nodes, bone marrow and Peyer's patches. Tolerance with respect to IgE can be induced by the injection of deaggregated ovalbumin into neonatal mice.
新生SWR小鼠在用伴刀豆球蛋白和卵清蛋白的混合物或百日咳博德特氏菌、明矾和卵清蛋白的混合物免疫时能够合成反应素。在脾脏、淋巴结、骨髓和派伊尔氏结中可发现产生反应素抗体的细胞。通过向新生小鼠注射去聚合的卵清蛋白可诱导对IgE的耐受性。
