Kos-Pietro S, Towle V L, Cakmur R, Spire J P
Department of Neurology, University of Chicago, USA.
Neuropediatrics. 1997 Dec;28(6):318-23. doi: 10.1055/s-2007-973723.
Visual evoked potentials to pattern reversal and diffuse flash stimulation were recorded from 520 consecutive pediatric patients and 11 normal infants between the ages of 27 weeks post-conception and 24 months. The latency and peak-to-peak amplitude of the first reproducible positive peak of the binocular pattern visual evoked potential (P100) were measured for five check sizes subtending from 15' to 4 degrees of arc. Three developmental trends were noted: 1) a rapid increase in pattern resolution near term, 2) a subsequent decrease in the latency of P100, and 3) a gradual increase in the amplitude of P100. These three trends reflect the multiplicity of early maturation and are discussed in terms of changes in receptor growth and density, pathway myelination, and cortical synaptivity.
对520例连续的儿科患者以及11名孕龄27周及24个月大的正常婴儿进行了图形翻转视觉诱发电位和弥散闪光刺激视觉诱发电位的记录。针对五种视角从15′至4度视角夹角的检查尺寸，测量了双眼图形视觉诱发电位（P100）首个可重复正峰的潜伏期和峰峰值幅度。观察到三种发育趋势：1）临近足月时图形分辨能力迅速提高；2）随后P100潜伏期缩短；3）P100幅度逐渐增大。这三种趋势反映了早期成熟的多样性，并从感受器生长和密度、通路髓鞘形成以及皮质突触活性的变化方面进行了讨论。
