Leduc Y, Drapeau S, Samson I, Tremblay R, Emond J G
Unité de Médecine Familiale de l'Enfant-Jésus, Centre Maizerets, Québec.
Can Fam Physician. 1997 Dec;43:2143-7.
To determine the prevalence of positive tuberculin tests in a population of patients requiring long-term care in a hospital setting. DESIGN: Prevalence study: to evaluate reaction to the test among patients who agreed to be included in the study. SETTING: The study took place in two units of the Enfant-Jésus hospital where patients are admitted for chronic care. PARTICIPANTS: A total of 108 patients were eligible for the study; 56 agreed to take part. One patient died before the study was completed. INTERVENTIONS: The tuberculin test consisted of an injection of PPD-T and reading the reaction 48 to 78 hours later. A reaction > 10 mm was considered significant. Patients with insignificant reactions were injected again 2 weeks later in order to evaluate positive response secondary to reactivation of the immune system (booster effect). MAIN OUTCOME MEASURES: Indications of previous tuberculosis, risk factors for tuberculosis, immunosuppressive medication, length of stay in hospital, size of reaction. RESULTS: Seventeen tuberculin tests were positive (30.9%); of these, six were positive after the second injection. CONCLUSION: The prevalence of positive tuberculin tests was high in our elderly population; this finding is comparable to the findings of American studies.
确定在医院环境中需要长期护理的患者群体中结核菌素试验阳性的患病率。
患病率研究:评估同意纳入研究的患者对该试验的反应。
研究在圣婴医院的两个科室进行,这些科室收治慢性护理患者。
共有108名患者符合研究条件;56名同意参与。1名患者在研究完成前死亡。
结核菌素试验包括注射PPD-T,并在48至78小时后读取反应。反应>10毫米被认为有意义。反应无意义的患者在2周后再次注射,以评估免疫系统重新激活后的阳性反应(增强效应)。
既往结核病的指征、结核病的危险因素、免疫抑制药物、住院时间、反应大小。
17例结核菌素试验呈阳性(30.9%);其中,6例在第二次注射后呈阳性。
我们老年人群中结核菌素试验阳性的患病率很高;这一发现与美国研究的结果相当。