氯化锂对某些精神类药物活性的影响。
The effect of lithium chloride on the activity of some psychotropic drugs.
作者信息
Wielosz M
出版信息
Pol J Pharmacol Pharm. 1976;28(2):189-98.
PMID:945563
Abstract
LiCl administered for 4 days enhances amphetamine-induced locomotor stimulation, increases amphetamine toxicity in aggregated mice but does not affect amphetamine stereotypy. Administered together with nialamide, LiCl increase locomotor activity of mice and rats. The administration of this compound together with reserpine reverses central effects of its action (hypothermia, decreased motility, enhancement of hexobarbital activity).
摘要
连续4天给予氯化锂可增强苯丙胺引起的运动兴奋，增加聚集小鼠对苯丙胺的毒性，但不影响苯丙胺引起的刻板行为。与尼亚酰胺一起给药时，氯化锂可增加小鼠和大鼠的运动活性。该化合物与利血平一起给药可逆转其作用的中枢效应（体温过低、运动减少、增强己巴比妥活性）。
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