Levy Y, George J, Abraham A, Afek A, Livneh A, Shoenfeld Y
The Department of Medicine B, Sheba Medical Center and Sackler Faculty of Medicine, Tel-Hashomer, Israel.
Clin Rheumatol. 1997 Nov;16(6):606-8. doi: 10.1007/BF02247801.
This case report describes an 81-year-old patient with prolonged rheumatoid arthritis (RA), which was complicated by the occurrence of a subcutaneous T-cell lymphoma. During the course of his illness the patient had not been treated with disease-modifying agents (i.e. cytotoxic agents), but only symptomatically with anti-inflammatory drugs. This finding demonstrates a previously undescribed association between RA and a rare from of subcutaneous T-cell lymphoma, which may add more information to the controversial issue of emergence of malignancy in RA.
本病例报告描述了一名81岁的类风湿性关节炎（RA）患者，该患者并发了皮下T细胞淋巴瘤。在其病程中，患者未接受过改善病情的药物（即细胞毒性药物）治疗，仅使用抗炎药物进行对症治疗。这一发现表明RA与一种罕见的皮下T细胞淋巴瘤之间存在此前未被描述的关联，这可能为RA中恶性肿瘤发生这一有争议的问题增添更多信息。
