Di Alberti L, Porter S R, Speight P M, Scully C M, Zakrzewska J M, Williams I G, Artese L, Piattelli A, Ngui S L, Teo C G
Department of Oral Medicine, Eastman Dental Institute, London, UK.
Oral Dis. 1997 May;3 Suppl 1:S133-4. doi: 10.1111/j.1601-0825.1997.tb00345.x.
To determine the frequency of detection of human herpesvirus-8 (HHV-8) in HIV-related oral ulcers.
Analysis of archived biopsy material.
Nested polymerase chain reaction of DNA extracts.
HHV-8 DNA was detected in six of 10 oral ulcers of HIV-positive patients without oral Kaposi's sarcoma (KS) lesions and five of 11 oral KS lesions. The positive non-KS samples were derived from various oral sites.
In HIV-positive people, HHV-8 can infect oral tissues that are not affected by KS.
