Pott W, Remschmidt H
Klinik und Poliklinik für Kinder- und Jugendpsychiatrie der Philipps-Universität Marburg.
Z Kinder Jugendpsychiatr Psychother. 1996 Dec;24(4):272-81.
Focal hypersynchronous activity in children with specific developmental deficits: Are there any clinical implications? To determine the frequency of focal hypersynchronous activity (HSA) in the EEGs of a child and adolescent psychiatry client population we evaluated 762 patients between 3 and 15 years old. Children with neurological problems, including epilepsy, craniocerebral trauma and psychotic disorders, and children on medication were excluded, as well as those with general developmental delays or abnormal EEG findings (except focal HSA). We then compared our data with those of two epidemiological investigations, in which 1.9% and 2.4%, respectively, of the children without psychiatric problems were found to have focal HSA. The children in our study with dyslexia or disorders of motor function had significantly higher rates of HSA. The boys with psychiatric findings (except those with speech and language disorders) appeared to have a higher rate of HSA. These findings support the hypothesis that focal HSA is probably an expression of a cerebral dysfunction of genetic origin. The symptomatology seems to depend on the moment of manifestation and the localization.
有哪些临床意义？为了确定儿童和青少年精神病患者群体脑电图中局灶性超同步活动（HSA）的频率，我们评估了762名3至15岁的患者。排除患有神经系统问题（包括癫痫、颅脑外伤和精神障碍）的儿童、正在服药的儿童以及有一般发育迟缓或脑电图异常结果（局灶性HSA除外）的儿童。然后，我们将我们的数据与两项流行病学调查的数据进行比较，在这两项调查中，分别有1.9%和2.4%没有精神问题的儿童被发现有局灶性HSA。我们研究中患有诵读困难或运动功能障碍的儿童HSA发生率显著更高。有精神症状的男孩（有言语和语言障碍的男孩除外）似乎HSA发生率更高。这些发现支持了这样一种假设，即局灶性HSA可能是遗传起源的脑功能障碍的一种表现。症状似乎取决于表现的时刻和定位。
