Burckhardt P, Bischof-Delaloye A, Ruedi B, Delaloye B
Acta Endocrinol (Copenh). 1976 Feb;81(2):298-309. doi: 10.1530/acta.0.0810298.
In 22 patients who underwent surgery suspected of primary hyperparathyroidism, the surgical findings were compared with the results obtained by pre-operative parathyroid scanning and biochemical screening. Thirteen of 15 parathyroid adenomas were localized by pre-operative scanning, but in five of them a false positive focus was also described. The technique was less useful in primary hyperplasia. Comparable results were reported by other investigators. In both instances the best results were obtained in patients with high parathyroid activity as measured by plasma calcium, plasma alkaline phosphatase and tubular reabsorption of phosphorus (TRP). Parathyroid scintigraphy was especially helpful in the presence of ectopic adenomas and in patients who had undergone previous parathyroid surgery. Unfortunately, the possibility of false positive results makes it unreliable for the diagnosis of primary hyperparathyroidism.
在22例接受疑似原发性甲状旁腺功能亢进手术的患者中，将手术结果与术前甲状旁腺扫描及生化筛查结果进行了比较。15例甲状旁腺腺瘤中有13例通过术前扫描定位，但其中5例还发现了假阳性病灶。该技术在原发性增生中不太有用。其他研究者也报告了类似结果。在这两种情况下，血浆钙、血浆碱性磷酸酶和磷的肾小管重吸收（TRP）所测得甲状旁腺活性较高的患者取得了最佳结果。甲状旁腺闪烁显像在异位腺瘤患者和既往接受过甲状旁腺手术的患者中特别有帮助。不幸的是，假阳性结果的可能性使其在原发性甲状旁腺功能亢进的诊断中不可靠。
