Hall A F, DeSchepper E, Ando M, Stookey G K
Glasgow Dental Hospital and School, Scotland.
Adv Dent Res. 1997 Nov;11(4):507-14. doi: 10.1177/08959374970110041901.
Laser fluorescence (LF) is thought to be a quantitative technique for the measurement of mineral loss from dental caries. These studies aimed to demonstrate the quantitative nature of LF, by means of transverse microradiography (TMR), in addition to the possible use of LF on small specimens suitable for in situ studies. Studies also aimed to determine the ability of LF to detect caries adjacent to amalgam restorations. The results demonstrated reasonable correlation between both the histological depth and mineral loss measured by TMR compared with the % change in mean fluorescence radiance measured by LF (r = 0.70 and 0.83, respectively). Studies with small specimens demonstrated that in vitro remineralization could be observed with LF for comparison of the demineralized specimen with an undemineralized reference. ANOVA showed significant mineral gain (p < 0.0001). The detection and quantification of mineral loss adjacent to amalgam restorations may have potential for the management of recurrent caries. Studies have demonstrated that LF can detect such mineral loss, and, with refinement of the image analysis system, LF was capable of detecting remineralization. Remineralization of such lesions is controversial, but it is suggested that LF may have a role in secondary caries management.
激光荧光（LF）被认为是一种用于测量龋齿矿物质流失的定量技术。这些研究旨在通过横向显微放射照相术（TMR）证明LF的定量特性，此外还研究了LF在适用于原位研究的小标本上的可能应用。研究还旨在确定LF检测汞合金修复体附近龋齿的能力。结果表明，与通过LF测量的平均荧光辐射率的百分比变化相比，TMR测量的组织学深度和矿物质流失之间存在合理的相关性（分别为r = 0.70和0.83）。对小标本的研究表明，通过LF可以观察到体外再矿化，以便将脱矿标本与未脱矿的对照进行比较。方差分析显示有显著的矿物质增加（p < 0.0001）。检测和量化汞合金修复体附近的矿物质流失可能对复发性龋齿的管理具有潜在意义。研究表明，LF可以检测到这种矿物质流失，并且随着图像分析系统的改进，LF能够检测到再矿化。这种病变的再矿化存在争议，但有人认为LF可能在继发性龋齿的管理中发挥作用。
