Naik S, Greenough A, Giffin F, Dimitriou G, Price J F
Department of Child Health, King's College Hospital, London, UK.
Acta Paediatr. 1997 Dec;86(12):1298-300. doi: 10.1111/j.1651-2227.1997.tb14901.x.
In a 9-y prospective study, the occurrence and duration of lung volume abnormalities in 21 young asthmatic children (median age at recruitment 4 y, range 3-8 y) was determined. The median functional residual capacity (FRC) at recruitment was 135% of that predicted for height (range 79-187%) and 13 children were hyperinflated. The median FRC decreased significantly after 3 y of follow-up and by 9 y only one child remained hyperinflated. We conclude that persistent elevation of lung volume in young asthmatic children appears to be uncommon.
在一项为期9年的前瞻性研究中,确定了21名年轻哮喘儿童(入组时的中位年龄为4岁,范围为3 - 8岁)肺容积异常的发生情况和持续时间。入组时的中位功能残气量(FRC)为身高预测值的135%(范围为79 - 187%),13名儿童存在肺过度充气。随访3年后,中位FRC显著下降,到9年时只有一名儿童仍存在肺过度充气。我们得出结论,年轻哮喘儿童肺容积持续升高似乎并不常见。