Greenough A, Loftus B G, Pool J, Price J F
Paediatric Respiratory Laboratory, King's College Hospital, London.
Thorax. 1987 Jul;42(7):500-5. doi: 10.1136/thx.42.7.500.
Measurements of total compliance of the respiratory system by the weighted spirometer technique and of the functional residual capacity by helium gas dilution were attempted in 86 asthmatic children aged 2.2-7.9 years. In all but six of the 86 children reliable measurements could be obtained. Significantly raised functional residual capacity was detected in children with asthma of all degrees of severity. The compliance of the respiratory system was significantly abnormal (reduced) only in children who had symptoms at the time of measurement or who had chronic persistent asthma. The results indicate that these measurements are well tolerated in young asthmatic children. Further work needs to be undertaken to assess the value of this technique in following the response to treatment.
采用重量式肺量计技术对86名年龄在2.2至7.9岁的哮喘儿童进行呼吸系统总顺应性测量，并通过氦气稀释法测量功能残气量。在这86名儿童中，除6名外，其余儿童均可获得可靠测量结果。在所有严重程度的哮喘儿童中均检测到功能残气量显著升高。仅在测量时出现症状或患有慢性持续性哮喘的儿童中，呼吸系统顺应性显著异常（降低）。结果表明，这些测量在年幼的哮喘儿童中耐受性良好。需要进一步开展工作以评估该技术在跟踪治疗反应方面的价值。
