Bunnell J E, Dumler J S, Childs J E, Glass G E
Johns Hopkins University, School of Hygiene and Public Health, Department of Molecular Microbiology and Immunology, Baltimore, Maryland 21205, USA.
J Wildl Dis. 1998 Jan;34(1):179-81. doi: 10.7589/0090-3558-34.1.179.
Archived serum samples from 111 Peromyscus leucopus, collected 1984-88 in Baltimore City (Maryland, USA), were analyzed by indirect immunofluorescence assay. Sera from two (2%) individuals contained antibodies reactive to Ehrlichia equi and the human granulocytic ehrlichiosis (HGE) agent. This suggests that the HGE agent or an antigenically related organism has been present in rodent populations in this locality for more than a decade, and was present in the region at least 12 yr before a case of human disease was recognized.
对1984年至1988年在美国马里兰州巴尔的摩市采集的111份白足鼠的存档血清样本进行了间接免疫荧光分析。两份(2%)个体的血清含有与马埃立克体和人类粒细胞埃立克体病(HGE)病原体反应的抗体。这表明,HGE病原体或一种抗原相关生物已在该地区的啮齿动物种群中存在了十多年,并且在人类疾病病例被确认之前至少12年就在该地区存在。