Tatto-Cano M I, Sanín-Aguirre L H, González V, Ruiz-Velasco S, Romieu I
Instituto Mexicano del Seguro Social (IMSS), Delegación Morelos, Cuernavaca, México.
Salud Publica Mex. 1997 Nov-Dec;39(6):497-506.
The measurement of asthma, rhinitis and eczema have been subject of controversy due to lack of a standardized methodology. To test the applicability of a standardized methodology for comparisons of time and space we determined the prevalence of asthma and other allergic diseases in a random sample of schoolchildren (n = 6,238) from 6 to 8 and 11 to 14 years of age living in Cuernavaca, Morelos, Mexico.
The methodology proposed by the International Study of Asthma and Allergies in Childhood (ISAAC) to determine prevalence and severity of asthma, rhinitis and eczema was applied. Current and accumulated information on prevalence was obtained by means of a standardized questionnaire answered by the children's parents.
The accumulated prevalence of asthma by medical diagnosis and wheezing was 5.8% (5.2-6.4) and 21.8% (20.7-22.9) respectively; prevalence of wheezing in the last 12 months was 8.9% in the group of 6 to 8 years against 6.6% in the 11 to 14 year old group p < 0.001. Prevalence of the medical diagnosis of rhinitis was 4.9% (4.3-5.5). Regarding the typical symptoms of rhinitis, in the last 12 months prevalence was 9.6% (6-8 years) and 10.1% (11-14 years). Prevalence of eczema by medical diagnosis was 4.1% (3.6-4.6). Prevalence of eczema symptoms in the last 12 months was 10.1% (6-8 years) and 10.6% (11-14 years). Prevalence of severe asthma symptoms was significantly higher in the 6 to 8 year olds and in the autumn.
Prevalence of asthma by medical diagnosis and by symptoms is relatively low with respect to other studies performed with the same methodology. The benefits of using a standardized methodology were analyzed.
由于缺乏标准化方法,哮喘、鼻炎和湿疹的测量一直存在争议。为了测试一种标准化方法在时间和空间比较中的适用性,我们在墨西哥莫雷洛斯州库埃纳瓦卡的6至8岁和11至14岁学童随机样本(n = 6,238)中确定了哮喘和其他过敏性疾病的患病率。
应用了国际儿童哮喘和过敏研究(ISAAC)提出的确定哮喘、鼻炎和湿疹患病率及严重程度的方法。通过儿童家长回答的标准化问卷获得了关于患病率的当前和累积信息。
经医学诊断的哮喘累积患病率和喘息患病率分别为5.8%(5.2 - 6.4)和21.8%(20.7 - 22.9);6至8岁组过去12个月的喘息患病率为8.9%,而11至14岁组为6.6%,p < 0.001。鼻炎医学诊断患病率为4.9%(4.3 - 5.5)。关于鼻炎的典型症状,过去12个月的患病率在6至8岁组为9.6%,在11至14岁组为10.1%。经医学诊断的湿疹患病率为4.1%(3.6 - 4.6)。过去12个月湿疹症状的患病率在6至8岁组为10.1%,在11至14岁组为10.6%。6至8岁儿童和秋季的严重哮喘症状患病率显著更高。
与采用相同方法进行的其他研究相比,经医学诊断和有症状的哮喘患病率相对较低。分析了使用标准化方法的益处。