两性霉素B对人中性粒细胞趋化性及化学发光的抑制作用。
Inhibition of human neutrophil chemotaxis and chemiluminescence by amphotericin B.
作者信息
Björkstén B, Ray C, Quie P G
出版信息
Infect Immun. 1976 Jul;14(1):315-7. doi: 10.1128/iai.14.1.315-317.1976.
Abstract
The effect of the antifungal drugs amphotericin B, fluocytosine, miconazole, griseofulvin, and nystatin on the chemotactic responsiveness of human neutrophils was studied. Amphotericin B in a concentration of 2 mug/ml inhibited chemotatic responsiveness, and in a concentration of 5 mug/ml it also inhibited chemiluminescence. The inhibition of chemotaxis could be reversed by washing the cells. The other antifungal drugs did not inhibit chemotaxis even in concentrations much higher than those obtained in human serum during treatment.
摘要
研究了抗真菌药物两性霉素B、氟胞嘧啶、咪康唑、灰黄霉素和制霉菌素对人中性粒细胞趋化反应性的影响。浓度为2微克/毫升的两性霉素B可抑制趋化反应性，浓度为5微克/毫升时还可抑制化学发光。通过洗涤细胞可逆转趋化性的抑制。其他抗真菌药物即使在浓度远高于治疗期间人血清中的浓度时也不抑制趋化性。
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本文引用的文献
1
Evidence for the generation of an electronic excitation state(s) in human polymorphonuclear leukocytes and its participation in bactericidal activity.人类多形核白细胞中电子激发态产生的证据及其在杀菌活性中的作用。
Biochem Biophys Res Commun. 1972 May 26;47(4):679-84. doi: 10.1016/0006-291x(72)90545-1.
2
Effects of tetracycline on leukotaxis.
J Infect Dis. 1974 Feb;129(2):110-6. doi: 10.1093/infdis/129.2.110.
3
Effect of tetracycline on the phagocytic function of human leukocytes.四环素对人白细胞吞噬功能的影响。
J Infect Dis. 1974 Oct;130(4):412-5. doi: 10.1093/infdis/130.4.412.
4
The ultrastructure of Candida albicans after in vitro treatment with miconazole.体外经咪康唑处理后白色念珠菌的超微结构
Sabouraudia. 1974 Nov;12(3):341-51.
5
Effects of 5-fluorocytosine on protein synthesis and amino acid pool in Candida albicans.
Sabouraudia. 1974 Nov;12(3):309-19. doi: 10.1080/00362177485380451.
6
Inhibition by sulfonamides of the candidacidal activity of human neutrophils.磺胺类药物对人中性粒细胞杀念珠菌活性的抑制作用。
J Clin Invest. 1971 Dec;50(12):2498-505. doi: 10.1172/JCI106750.
7
8
Modulation of human neutrophil chemotactic responses by cyclic 3',5'-guanosine monophosphate and cyclic 3',5'-adenosine monophosphate.环3',5'-鸟苷单磷酸和环3',5'-腺苷单磷酸对人中性粒细胞趋化反应的调节
Metabolism. 1975 Mar;24(3):447-56. doi: 10.1016/0026-0495(75)90124-9.
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