Hauswirth W A, Oehler M, Rüther G, Walther-Wenke G
DRK-Blutspendedienst, Institut Münster, Deutschland.
Beitr Infusionsther Transfusionsmed. 1994;32:88-91.
Ten years of quality control in routine have led to a standardized platelet concentrate (PC). Mean parameters of the preparations are in the range of pH 6.7-7.3, (1.0-1.5) x 10(9)/ml platelet concentration, 80 x 10(9) platelets/PC and 2 x 10(7) leukocytes/PC. To judge the function of PCs, three methods were compared: the morphologic score, platelet aggregation tests, and the hypotonic shock reaction. The result is: The hypotonic shock reaction is a simple, well reproducible and sensitive method to judge the cell integrity.
十年来的常规质量控制已造就了标准化的血小板浓缩物（PC）。制剂的平均参数范围为pH值6.7 - 7.3、血小板浓度（1.0 - 1.5）×10⁹/ml、每单位PC含80×10⁹个血小板以及每单位PC含2×10⁷个白细胞。为评估血小板浓缩物的功能，比较了三种方法：形态学评分、血小板聚集试验和低渗休克反应。结果是：低渗休克反应是一种判断细胞完整性的简单、可重复性好且敏感的方法。
