Griton P, Vanet P, Cloarec M
Unité de Phlébologie-Angiologie, Hôpital Tenon, Paris.
J Mal Vasc. 1997 May;22(2):97-100.
The comparison of the venous system in the human organism, and in particular the venous valves of the lower limbs, with studies conducted in animal models helped us to understand better the mechanisms involved in adapting to the upright position and walking. We examined work conducted in several species from the horse to the dog, especially in animals who often take on an upright position such as the chimpanzee and the kangouroo, in search for structures comparable to those in man. Different types of valves can be described in man: flotting valves (bicuspid, pigeon nest valves); reinforced valves (mid-thigh); reinforcing valves (periarticular zone in the knee); finally, "flat" valves which are highly resistant formations but with little anti-back flow action. We also describe valvular structures with muscle cells found in the plantar aspect of the foot and the veins of the quadriceps muscle, these valves may have an active hematopropulsive action (Bassi). These results allowed us to identify certain common points between the structures observed in the posterior legs of certain animals and to propose models for investigating venous diseases.
将人体静脉系统,尤其是下肢静脉瓣膜,与在动物模型中进行的研究作比较,有助于我们更好地理解适应直立姿势和行走所涉及的机制。我们研究了从马到狗等几个物种的相关情况,特别是像黑猩猩和袋鼠这类经常采取直立姿势的动物,以寻找与人类相似的结构。在人类中可描述出不同类型的瓣膜:浮动瓣膜(双尖瓣、鸽巢瓣膜);强化瓣膜(大腿中部);加强瓣膜(膝盖周围区域);最后是“扁平”瓣膜,它们是高度抗阻的结构,但抗反流作用较小。我们还描述了在足底和股四头肌静脉中发现的带有肌肉细胞的瓣膜结构,这些瓣膜可能具有主动的血液推进作用(巴西)。这些结果使我们能够确定某些动物后腿中观察到的结构之间的某些共同点,并提出用于研究静脉疾病的模型。