Jones C J, Fox H
Obstet Gynecol. 1976 Sep;48(3):274-80.
A light microscopic, an electron microscopic, and a ultrahistochemical study have been made of seven placentas from women with mild and excellently controlled chemical gestational diabetes. Only one placenta showed no significant abnormality; the remainder showed, to a varying degree, changes in the syncytiotrophoblast, cytotrophoblast, trophoblastic basement membrane, and fetal vessels. These abnormalities were identical to and in some cases as severe as those found in placentas from women with longstanding, moderately controlled, overt diabetes mellitus. These findings indicate that control of hyperglycemia only partially prevents the development of placental abnormalities which must be due to some other constituent factor of the diabetic state.
对7例患有轻度且血糖控制极佳的化学性妊娠糖尿病女性的胎盘进行了光镜、电镜和超组织化学研究。只有1个胎盘未显示明显异常；其余胎盘在不同程度上显示出合体滋养层、细胞滋养层、滋养层基底膜和胎儿血管的变化。这些异常与长期中度控制的显性糖尿病女性胎盘中发现的异常相同，在某些情况下同样严重。这些发现表明，高血糖的控制只能部分预防胎盘异常的发生，而胎盘异常肯定是由糖尿病状态的其他一些构成因素引起的。
