人类乳腺肿瘤诱导的骨溶解与前列腺素
Human breast tumour-induced osteolysis and prostaglandins.
作者信息
Dowsett M, Easty G C, Powles T J, Easty D M, Neville A M
出版信息
Prostaglandins. 1976 Mar;11(3):447-60. doi: 10.1016/0090-6980(76)90078-2.
PMID:948618
Abstract
Osteolysis effected in vitro by breast carcinomas can be inhibited by aspirin. Some prostaglandins stimulate in vitro bone resorption. Our results indicate that whilst osteolytically active PGE and PGF are released by the carcinomas in most cases, some other osteolytic principle is released as well.
摘要
乳腺癌在体外引起的骨质溶解可被阿司匹林抑制。一些前列腺素在体外刺激骨吸收。我们的结果表明，虽然大多数情况下癌组织会释放具有溶骨活性的前列腺素E和前列腺素F，但也会释放其他一些溶骨因子。
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