粪便中前列腺素样物质的测定及其在溃疡性结肠炎中的测量
Assay of prostaglandin-like substances in faeces and their measurement in ulcerative colitis.
作者信息
Gould S R
出版信息
Prostaglandins. 1976 Mar;11(3):489-97. doi: 10.1016/0090-6980(76)90095-2.
PMID:948621
Abstract
A method is described for extracting and measuring prostaglandin-like substances from faeces. Bioassay has shown virtual absence of activity in stools from normal people (8 subjects) but raised levels in stools from patients with active ulcerative colitis (16 observations on 6 patients). The relevance of these observations to the mode of action of sulphasalazine is discussed and suggestions for possible applications of this method to other problems made.
摘要
本文描述了一种从粪便中提取和测量类前列腺素物质的方法。生物测定表明，正常人（8名受试者）的粪便中几乎没有活性，但活动期溃疡性结肠炎患者的粪便中活性水平升高（对6名患者进行了16次观察）。讨论了这些观察结果与柳氮磺胺吡啶作用方式的相关性，并提出了将该方法应用于其他问题的可能建议。
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