HLA transgenic mice as humanized mouse models of disease and immunity.
作者信息
Taneja V, David C S
机构信息
Department of Immunology, Mayo Clinic, Rochester, Minnesota 55905, USA.
出版信息
J Clin Invest. 1998 Mar 1;101(5):921-6. doi: 10.1172/JCI2860.
Abstract
摘要
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本文引用的文献
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T cell recognition of human pre-proinsulin peptides depends on the polymorphism at HLA DQ locus: a study using HLA DQ8 and DQ6 transgenic mice.人类胰岛素原前体肽的T细胞识别取决于HLA DQ基因座的多态性：一项使用HLA DQ8和DQ6转基因小鼠的研究。
Hum Immunol. 1997 Nov;58(1):21-9. doi: 10.1016/s0198-8859(97)00212-7.
2
HLA-DQB1 polymorphism determines incidence, onset, and severity of collagen-induced arthritis in transgenic mice. Implications in human rheumatoid arthritis.HLA-DQB1基因多态性决定转基因小鼠胶原诱导性关节炎的发病率、发病情况及严重程度。对人类类风湿关节炎的启示。
J Clin Invest. 1997 Nov 1;100(9):2227-34. doi: 10.1172/JCI119760.
3
Expression of the H2-E molecule mediates protection to collagen-induced arthritis in HLA-DQ8 transgenic mice: role of cytokines.H2-E分子的表达介导HLA-DQ8转基因小鼠对胶原诱导性关节炎的保护作用：细胞因子的作用
Int Immunol. 1997 Aug;9(8):1213-9. doi: 10.1093/intimm/9.8.1213.
4
Identification of immunodominant T cell epitopes of human glutamic acid decarboxylase 65 by using HLA-DR(alpha1*0101,beta1*0401) transgenic mice.利用HLA-DR（α1*0101，β1*0401）转基因小鼠鉴定人谷氨酸脱羧酶65的免疫显性T细胞表位。
Proc Natl Acad Sci U S A. 1997 Jul 22;94(15):8082-7. doi: 10.1073/pnas.94.15.8082.
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An HLA-DR1 transgene confers susceptibility to collagen-induced arthritis elicited with human type II collagen.HLA - DR1转基因使人对由人II型胶原蛋白引发的胶原诱导性关节炎易感。
J Exp Med. 1997 Mar 17;185(6):1113-22. doi: 10.1084/jem.185.6.1113.
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HLA-DRB1 polymorphism determines susceptibility to autoimmune thyroiditis in transgenic mice: definitive association with HLA-DRB1*0301 (DR3) gene.HLA - DRB1基因多态性决定转基因小鼠对自身免疫性甲状腺炎的易感性：与HLA - DRB1*0301（DR3）基因存在明确关联。
J Exp Med. 1996 Sep 1;184(3):1167-72. doi: 10.1084/jem.184.3.1167.
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Immunogenicity and contraceptive potential of a human zona pellucida 3 peptide vaccine.人透明带蛋白3肽疫苗的免疫原性及避孕潜力
Biol Reprod. 1997 Mar;56(3):764-70. doi: 10.1095/biolreprod56.3.764.
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HLA-B27 heavy chains contribute to spontaneous inflammatory disease in B27/human beta2-microglobulin (beta2m) double transgenic mice with disrupted mouse beta2m.HLA - B27重链在小鼠β2微球蛋白（β2m）基因敲除的B27/人β2微球蛋白（β2m）双转基因小鼠中引发自发性炎症疾病。
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10
Naturally processed T cell epitopes from human glutamic acid decarboxylase identified using mice transgenic for the type 1 diabetes-associated human MHC class II allele, DRB1*0401.利用针对1型糖尿病相关人类MHC II类等位基因DRB1*0401转基因的小鼠鉴定出的来自人谷氨酸脱羧酶的天然加工T细胞表位。
J Clin Invest. 1996 Dec 1;98(11):2597-603. doi: 10.1172/JCI119079.
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