Mucklow E S
Paediatric Department, St Mary's Hospital, Newport, Isle of Wight, UK.
Int J Clin Pract. 1997 Jul-Aug;51(5):321-3.
A prospective survey of chemistry set poisoning (CSP) was undertaken using the monthly postal enquiry report system of the British Paediatric Surveillance Unit (BPSU). Fourteen cases were reported, with one fatality and uneventful full recovery in the other 13. The packaging of the chemicals was unsatisfactory in all cases: it was not child resistant and had no proper closures. Risk factors were lack of supervision 64.3%, emotional factors 28.6%, genuine accident 7% and unidentified 7%. An additional retrospective survey of CSP reported to the National Poisons Information Service centres over the same period added a further 19 cases of CSP, making a total of 33 cases, 14 (42%) being due to copper sulphate and four (12%) to cobalt chloride, respectively. This survey showed CSP to be a significant problem, with an incidence of 0.3 cases per 100,000 children. Six recommendations were made concerning child-resistant containers, toxic hazard warnings, size and content of the lettering, health education programmes targeted at the most vulnerable groups, and lastly, a legal restriction on the chemicals that can be included in these sets, so that the most toxic are excluded.
利用英国儿科监测单位(BPSU)的月度邮政询问报告系统,对化学套装中毒(CSP)进行了一项前瞻性调查。共报告了14例病例,其中1例死亡,其他13例完全康复且无并发症。所有病例中化学物质的包装均不令人满意:不具备儿童防护功能,且没有合适的密封措施。危险因素包括缺乏监管(64.3%)、情绪因素(28.6%)、真正的意外事故(7%)以及不明原因(7%)。同期向国家毒物信息服务中心报告的CSP的另一项回顾性调查又增加了19例CSP病例,共计33例,其中分别有14例(42%)由硫酸铜引起,4例(12%)由氯化钴引起。这项调查表明CSP是一个重大问题,发病率为每10万名儿童中有0.3例。针对儿童防护容器、有毒危害警告、字体大小和内容、针对最脆弱群体的健康教育计划,以及最后对可包含在这些套装中的化学物质的法律限制(以便排除毒性最强的物质)提出了六项建议。