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[产肠毒素特性与大肠杆菌抗原结构的相互关系]

[Interrelation of the enterotoxigenic properties and the antigenic structure of Escherichia].

作者信息

Romanenkova N I, Khazenson L B, Stanislavskiĭ E S, Ulisko I N

出版信息

Zh Mikrobiol Epidemiol Immunobiol. 1986 Feb(2):38-41.

PMID:3962536
Abstract

The enzymatic signs and serological characteristics of Escherichia enterotoxigenic strains isolated from patients with acute intestinal diseases and from healthy persons were studied. The cultures were subdivided into 24 enzymatic variants and classified with 48 serogroups and 61 serovars. The enterotoxigenic properties of the strains were compared with their serological characteristics and enzymatic signs. The strains, isolated from different persons and classified with the same serovar, belonged to the same variant with respect to the type of enterotoxin they produced (only thermostable enterotoxin, only thermolabile enterotoxin, or both), were similar in the degree of their toxigenicity and belonged, as a rule, to the same enzymatic variant. The data on the presence of manifest interrelation between the enteropathogenicity of Escherichia and their structure, as well as on the stability of the enterotoxigenic properties of these organisms, indicate that in acute intestinal diseases the determination of Escherichia enterotoxigenic strains can be carried out by common bacteriological techniques with the use of specific agglutinating sera.

摘要

对从急性肠道疾病患者和健康人分离出的产肠毒素大肠杆菌菌株的酶学特征和血清学特性进行了研究。这些培养物被细分为24种酶变体,并分为48个血清群和61个血清型。将菌株的产肠毒素特性与其血清学特征和酶学特征进行了比较。从不同人分离出并归为同一血清型的菌株,就其所产生的肠毒素类型(仅耐热肠毒素、仅不耐热肠毒素或两者兼有)而言,属于同一变体,其产毒程度相似,并且通常属于同一酶变体。关于大肠杆菌的肠致病性与其结构之间明显存在相互关系的数据,以及关于这些生物体产肠毒素特性稳定性的数据表明,在急性肠道疾病中,产肠毒素大肠杆菌菌株的鉴定可以通过使用特异性凝集血清的常规细菌学技术来进行。

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