Mogi G, Maeda S, Yoshida T, Watanabe N
Acta Otolaryngol. 1976 Jul-Aug;82(1-2):26-32. doi: 10.3109/00016487609120859.
Fifty-six sample pairs of middle ear effusions and sera obtained from patients with otitis media with effusion were investigated for The IgE antibody activity against mites, using radioallergosorbent test (RAST) which was recently developed as an in vitro allergy test. The IgE concentrations were also determined by radioimmunosorbent test (RIST). Results showed that the IgE antibody activity against this allergen was found in 5 middle ear effusions and 3 sera. Four of 5 patients with the positive RAST test had nasal allergy or signs suggesting allergy. Theree were two middle ear effusions which seemed to be an allergic fluid. However, findings in the present study do not suggest that middle ear effusions result from the direct allergic reaction induced by mites in the mucous membrane lining the middle ear cavity.
采用最近开发的体外过敏试验——放射变应原吸附试验（RAST），对56对从中耳积液患者获取的中耳积液样本和血清样本进行了针对螨虫的IgE抗体活性研究。同时，采用放射免疫吸附试验（RIST）测定了IgE浓度。结果显示，在5份中耳积液和3份血清中发现了针对该变应原的IgE抗体活性。5例RAST试验阳性的患者中有4例患有鼻过敏或有提示过敏的体征。有两份中耳积液似乎是过敏性液体。然而，本研究结果并不表明中耳积液是由中耳腔黏膜中螨虫引起的直接过敏反应所致。
