Yamasaki K, Suematsu H, Takahashi T
Chemicals Inspection and Testing Institute, Hita, Japan.
J Am Vet Med Assoc. 1998 Feb 15;212(4):529-33.
To determine prevalence of gastric spiral organisms (GSO) in dogs and cats that were clinically normal or had primary gastrointestinal disease and to compare histologic lesions of the stomach in dogs and cats with and without GSO.
21 dogs and 10 cats that were clinically normal and 56 dogs and 33 cats with gastrointestinal disease.
Case-control study.
Unevenness of the gastric mucosal surface was detected, using endoscopic techniques in 20 and 25% of clinically normal and abnormal dogs, respectively. On histologic examination, GSO were located on the mucosal surface within or beneath the mucus, in gastric pits, and within glandular lumina in 86 and 90% of clinically normal dogs and cats, respectively, and in 61 and 64% of clinically abnormal dogs and cats, respectively. Prevalence of GSO infection in dogs and cats that were clinically abnormal was not higher than in those that were clinically normal. Infection was detected in stomachs of > 60% of dogs and cats 1 year old or less. Helicobacter pylori was not isolated from any specimen; however, specimens in which GSO were found had positive results on a urease test.
Prevalence of GSO infection was high in clinically normal and abnormal dogs and cats, some of which were young. This should be considered during assessment of clinically normal animals with GSO as they can be a potential reservoir for infection in human beings.
确定临床正常或患有原发性胃肠疾病的犬猫中胃螺旋菌（GSO）的患病率，并比较有无GSO的犬猫胃的组织学病变。
21只临床正常的犬、10只临床正常的猫、56只患有胃肠疾病的犬和33只患有胃肠疾病的猫。
病例对照研究。
分别在20%的临床正常犬和25%的临床异常犬中，使用内镜技术检测到胃黏膜表面不平整。组织学检查显示，在临床正常的犬和猫中，分别有86%和90%的GSO位于黏液内或其下方的黏膜表面、胃小凹及腺腔内，在临床异常的犬和猫中，这一比例分别为61%和64%。临床异常的犬猫中GSO感染的患病率并不高于临床正常的犬猫。在1岁及以下的犬猫中，超过60%的胃检测到感染。未从任何标本中分离出幽门螺杆菌；然而，发现有GSO的标本尿素酶试验呈阳性。
临床正常和异常的犬猫中GSO感染的患病率都很高，其中一些是幼龄动物。在评估携带GSO的临床正常动物时应考虑到这一点，因为它们可能是人类感染的潜在传染源。
