Virstiuk N H
Lik Sprava. 1997 Sep-Oct(5):166-70.
Patients with rheumatic arthritis displayed alterations in blood serum fatty acid spectrum such that polyunsaturated fatty acids tended to be on the decrease, arachidonic acid in particular, monounsaturated ones on the increase. Long-term aurotherapy (for up to 1.5 yr) made for normalization of serum content of unsaturated fatty acids, which observation was accompanied by clinical-and-laboratory remission of rheumatic arthritis. Crisanole effect got higher with incrementing dosage of metallic gold. Results of studies made pathogenetically validate the expediency of long-term aurotherapy in patients with rheumatic arthritis.
风湿性关节炎患者血清脂肪酸谱发生改变，多不饱和脂肪酸呈减少趋势，尤其是花生四烯酸，单不饱和脂肪酸则呈增加趋势。长期金疗法（长达1.5年）可使血清不饱和脂肪酸含量恢复正常，这一现象伴随着风湿性关节炎的临床和实验室缓解。随着金属金剂量的增加，克立沙诺尔效应增强。研究结果从发病机制上证实了长期金疗法对风湿性关节炎患者的合理性。
