Engleman H M, Hirst W S, Douglas N J
Department of Medicine (RIE), University of Edinburgh, UK.
J Sleep Res. 1997 Dec;6(4):272-5. doi: 10.1111/j.1365-2869.1997.00272.x.
Under reporting of symptoms by patients with sleep apnoea/hypopnoea syndrome (SAHS) has been reported anecdotally, but investigation of the prevalence or determinants of this is limited. To assess this, repeated ratings in 99 patients with sleep apnoea/hypopnoea syndrome of pre-treatment Epworth sleepiness score, unintended napping, driving impairment and mood were obtained, first at presentation and then after treatment with continuous positive airway pressure (CPAP) therapy of median 22 (range 2-70) weeks duration. Median Epworth score for pre-treatment sleepiness rose from 12 (range 0-24) initially to 14 (range 5-24) retrospectively (P<0.0001). More patients initially under-rated Epworth score (67%) than over-rated (29%; P<0.001). 'False negative' cases with an initially 'normal' (< or = 10) and retrospectively 'sleepy' (> or = 11) Epworth score comprised 24% of all patients and 62% of initially 'normal' scorers. Unintended napping behaviour also was rated as significantly more severe on retrospective assessment (P<0.001). Driving impairment due to sleepiness was initially reported by 23% of all drivers and retrospectively by 37% (P=0.01), with 25% of initial deniers retrospectively admitting compromised driving ability before continuous positive airway pressure. No polysomnographic predictors of symptom under reporting were found (P>0.1). These results suggest a high prevalence of symptom minimization before treatment in patients with sleep apnoea/hypopnoea syndrome.
有传闻称睡眠呼吸暂停/低通气综合征(SAHS)患者对症状的报告不足,但对此现象的患病率或决定因素的研究有限。为了评估这一点,我们对99例睡眠呼吸暂停/低通气综合征患者进行了重复评分,分别在初诊时以及接受持续气道正压通气(CPAP)治疗中位数为22周(范围2 - 70周)后,对治疗前的Epworth嗜睡评分、意外小睡、驾驶能力受损和情绪进行评估。治疗前嗜睡的Epworth评分中位数从最初的12分(范围0 - 24分)升至回顾性评分的14分(范围5 - 24分)(P<0.0001)。最初低估Epworth评分的患者(67%)多于高估的患者(29%;P<0.001)。最初Epworth评分“正常”(≤10分)而回顾性评分“嗜睡”(≥11分)的“假阴性”病例占所有患者的24%,占最初“正常”评分者的62%。回顾性评估时,意外小睡行为的严重程度也被评定为显著更高(P<0.001)。所有驾驶者中,最初有23%报告因嗜睡导致驾驶能力受损,回顾性报告为37%(P = 0.01),25%最初否认者在接受持续气道正压通气治疗前回顾性承认驾驶能力受损。未发现多导睡眠图可预测症状报告不足(P>0.1)。这些结果表明,睡眠呼吸暂停/低通气综合征患者在治疗前症状最小化的患病率很高。