López Alcina E, Rodrígo Aliaga M, Martínez Jabaloyas J M, Arlandis Guzmán A, Del Pino Porres J, Jiménez Cruz F
Servicio de Urología, Hospital La Fe, Valencia.
Actas Urol Esp. 1997 Nov-Dec;21(10):956-60.
Extragonadal germ cells tumors can arise primarily in the retroperitoneum. It has been suggested that these neoplasms might be metastasis from an occult testicular lesion which would have regressed later. We report our experience with seven retroperitoneal germ cell tumors without testicular involvement. The most frequent symptoms were lumbar or abdominal pain and paraneoplastic syndrome. Abdominal palpable mass was noticeable in 85% of patients. We point out the computerized tomography and echography as the most sensitive exploration for diagnosis. The confirmation of retroperitoneal tumor was achieved preoperatively in all cases. Surgical and chemotherapy treatment was performed. Radiotherapy was employed in two cases. The mean survival was 9.5 months (6-24 m.). Retroperitoneal lymphadenectomy after chemotherapy has not improved the survival. Relapses of the diseases were noticed after and apparently partial or complete response to chemotherapy.
性腺外生殖细胞肿瘤可原发于腹膜后。有人提出，这些肿瘤可能是来自隐匿性睾丸病变的转移灶，而该睾丸病变随后可能已经消退。我们报告了7例无睾丸受累的腹膜后生殖细胞肿瘤的治疗经验。最常见的症状是腰腹痛和副肿瘤综合征。85%的患者可触及腹部肿块。我们指出，计算机断层扫描和超声检查是诊断最敏感的检查方法。所有病例术前均确诊为腹膜后肿瘤。进行了手术和化疗。2例采用了放疗。平均生存期为9.5个月（6 - 24个月）。化疗后行腹膜后淋巴结清扫术并未提高生存率。在对化疗有明显部分或完全反应后，疾病出现复发。
