Shashikanth M C, Rao B B
Department of Oral Medicine and Radiology, Bapuji Dental College, Davangere.
Indian J Dent Res. 1994 Oct-Dec;5(4):119-24.
Serum fucose and sialic acid levels were determined in 50 oral cancer patients and 25 healthy controls. A statistically significant increase was noted in the study group. The increase in serum fucose level correlated well with the clinical staging in the study group whereas sialic acid did not. These values were independent of age, sex and histopathological grading. The result suggest that the serum fucose level is a better biochemical tumor marker than sialic acid level. However its usefulness may be limited if used judiciously to assess the prognosis of the disease.
对50例口腔癌患者和25名健康对照者测定了血清岩藻糖和唾液酸水平。研究组中观察到有统计学意义的升高。研究组中血清岩藻糖水平的升高与临床分期密切相关，而唾液酸则不然。这些值与年龄、性别和组织病理学分级无关。结果表明，血清岩藻糖水平是比唾液酸水平更好的生化肿瘤标志物。然而，如果明智地使用它来评估疾病的预后，其有用性可能会受到限制。
