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急性心肌梗死后急诊冠状动脉旁路移植术。哪些因素影响术后早期死亡率?

Emergency coronary artery bypass grafting after acute myocardial infarction. What influences early postoperative mortality?

作者信息

Yamagishi I, Sakurada T, Abe T

机构信息

Department of Cardiovascular Surgery, Akita Medical Center, 6-17 Senshu Kubotamachi, Akita 010-0874, Japan.

出版信息

Ann Thorac Cardiovasc Surg. 1998 Feb;4(1):28-33.

PMID:9495904
Abstract

Although short- and long-term outcomes after elective coronary artery bypass grafting (CABG) has improved, emergency CABG after acute myocardial infarction (AMI) does not always bring satisfactory prognosis. In this report, early postoperative and follow-up results were studied. Furthermore, variables related to hospital mortality were explored. From among 186 patients who underwent CABG, 18 patients formed the basis of this research. This series included 16 males and 2 females, with a mean age of 65.3 years old. Hospital mortality of the patients was 38.9%, and actual survival rate of all the patients 5 years after CABG was 55.6%. Factors that predicted hospital mortality in those patients included increased age and preoperative cardiogenic shock. There was no difference in hospital mortality between the patients operated on with only saphenous vein (SV) and those operated on in combination with SV and internal thoracic artery (ITA). In emergency CABG, cardiogenic shock before surgery was most likely to influence hospital mortality. Therefore, an appropriate circulatory support system should be applied to improve hemodynamic status before bypass surgery.

摘要

尽管择期冠状动脉旁路移植术(CABG)后的短期和长期预后有所改善,但急性心肌梗死(AMI)后的急诊CABG并不总能带来令人满意的预后。在本报告中,研究了术后早期及随访结果。此外,还探讨了与医院死亡率相关的变量。在186例行CABG的患者中,18例构成了本研究的基础。该系列包括16名男性和2名女性,平均年龄65.3岁。患者的医院死亡率为38.9%,CABG术后5年所有患者的实际生存率为55.6%。预测这些患者医院死亡率的因素包括年龄增加和术前心源性休克。仅采用大隐静脉(SV)进行手术的患者与采用SV和胸廓内动脉(ITA)联合进行手术的患者在医院死亡率方面没有差异。在急诊CABG中,术前心源性休克最有可能影响医院死亡率。因此,应应用适当的循环支持系统以改善旁路手术前的血流动力学状态。

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