Abu-Elteen K H, Abu-Alteen R M
Department of Medical Technology, Al-Zaytoonah University, Amman, Jordan.
New Microbiol. 1998 Jan;21(1):41-8.
Using imprint cultures, the prevalence of oral candidosis and the frequency of isolation of Candida albicans and its density in oral mucosal sites and denture surfaces was determined in 190 healthy dentate subjects and 230 complete denture wearers. Candida colonization was 36.8% and 78.3% in healthy dentate and complete denture wearers patients, respectively. In the healthy dentate subjects the tongue, palate and cheeks, and in complete denture wearers additionally the upper and lower dentures, were the most frequently and densely colonized oral sites. Oral carrier rate and density of C. albicans were both higher in the denture wearers diabetic group than in the control non-diabetic group. Smoking was associated with an increase in the frequency and density of the yeast in denture wearers. Attention to these predisposing factors could reduce the incidence of oral candidosis particularly in immunocompromised patients.
通过印迹培养法，在190名健康有牙受试者和230名全口义齿佩戴者中，测定了口腔念珠菌病的患病率、白色念珠菌的分离频率及其在口腔黏膜部位和义齿表面的密度。健康有牙患者和全口义齿佩戴者的念珠菌定植率分别为36.8%和78.3%。在健康有牙受试者中，舌、腭和颊部，以及在全口义齿佩戴者中，上、下义齿是念珠菌定植最频繁且密度最高的口腔部位。义齿佩戴者糖尿病组的白色念珠菌口腔携带率和密度均高于非糖尿病对照组。吸烟与义齿佩戴者酵母菌的频率和密度增加有关。关注这些易感因素可降低口腔念珠菌病的发病率，尤其是在免疫功能低下的患者中。
