在患有脑部疾病的免疫功能正常个体的脑脊液中检测爱泼斯坦-巴尔病毒DNA。

Detection of Epstein-Barr virus DNA in cerebrospinal fluid from immunocompetent individuals with brain disorders.

作者信息

Portolani M, Pietrosemoli P, Meacci M, Sabbatini A M, Pecorari M, Mantovani G, Cermelli C

机构信息

Department of Biomedical Sciences, University of Modena, Italy.

出版信息

New Microbiol. 1998 Jan;21(1):77-9.

PMID:9497932

Abstract

Fifty four cerebrospinal fluid samples obtained from as many immunocomponent patients with disorders of the central nervous system were investigated for the presence of herpesvirus DNA by nested polymerase chain reaction in order to determine an etiological diagnosis. Four of these samples proved positive for the presence of Epstein-Barr virus DNA (7.4%). The result of this diagnostic study is reported to draw insiders' attention to the possible presence of EBV in cerebrospinal fluid from patients with central nervous system diseases.

摘要

为了进行病因诊断，通过巢式聚合酶链反应对从54名患有中枢神经系统疾病的免疫功能正常患者中获取的54份脑脊液样本进行了研究，以检测疱疹病毒DNA的存在。其中4份样本被证明存在爱泼斯坦-巴尔病毒DNA（7.4%）。报告这项诊断研究的结果是为了引起业内人士对中枢神经系统疾病患者脑脊液中可能存在EBV的关注。