Craven D E, Duncan R A, Stram J R, O'Hara C J, Steger K A, Jhamb K, Hirschhorn L R
Boston University School of Medicine, Boston Medical Center, Massachusetts 02118, USA.
Ann Intern Med. 1998 Mar 15;128(6):455-9. doi: 10.7326/0003-4819-128-6-199803150-00006.
Surgical resection has been the usual therapy for HIV-infected patients with lymphoepithelial parotid cysts.
To study antiretroviral therapy for lymphoepithelial parotid cysts.
Case series.
HIV outpatient clinics.
HIV-infected patients with lymphoepithelial parotid cysts.
Antiretroviral therapy.
Change in size of the parotid cyst, CD4 lymphocyte count, and HIV viral load.
Nine HIV-infected adults presented with chronic, large parotid cysts, eight of which were bilateral. In at least seven patients, the cysts were the initial sign of HIV infection. In six patients, the cysts resolved completely with combination antiretroviral therapy. Four of these patients also received prednisone. Three patients who did not comply with antiretroviral therapy had partial responses followed by relapses.
Parotid cysts are an unrecognized sign of early HIV infection. These cysts respond to combination antiretroviral therapy, with or without corticosteroids. Surgical resection should be reserved for patients in whom medical therapy has failed or those who refuse or are poorly compliant with medical therapy.
手术切除一直是感染人类免疫缺陷病毒（HIV）的淋巴上皮性腮腺囊肿患者的常用治疗方法。
研究抗逆转录病毒疗法治疗淋巴上皮性腮腺囊肿的效果。
病例系列。
HIV门诊。
感染HIV且患有淋巴上皮性腮腺囊肿的患者。
抗逆转录病毒疗法。
腮腺囊肿大小的变化、CD4淋巴细胞计数和HIV病毒载量。
9名感染HIV的成年人患有慢性、大型腮腺囊肿，其中8例为双侧囊肿。至少7名患者的囊肿是HIV感染的初始症状。6例患者通过联合抗逆转录病毒疗法囊肿完全消退。其中4例患者还接受了泼尼松治疗。3例未坚持抗逆转录病毒治疗的患者有部分反应，随后复发。
腮腺囊肿是早期HIV感染未被认识的体征。这些囊肿对抗逆转录病毒联合疗法有反应，无论是否使用皮质类固醇。手术切除应保留给药物治疗失败的患者或拒绝药物治疗或依从性差的患者。
