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伴有复发性急性胰腺炎和非结合性高胆红素血症且无明显溶血的急性间歇性卟啉病。

Acute intermittent porphyria with relapsing acute pancreatitis and unconjugated hyperbilirubinemia without overt hemolysis.

作者信息

Kobza K, Gyr K, Neuhaus K, Gudat F

出版信息

Gastroenterology. 1976 Sep;71(3):494-6.

PMID:950100
Abstract

A 36-year-old woman was admitted to hospital with a first attack of acute intermittent porphyria. At the same time increased serum levels of amylase and lipase as well as an increased amylase clearance to creatinine clearance ratio were observed, permitting the diagnosis of acute pancreatitis. The etiology of the latter could not be determined. In addition, elevation of indirect bilirubin without evidence of hemolysis was observed Gilbert's syndrome was suspected. 40 weeks after the first episode, a second attack of identical abdominal pain was noted, with elevation of pancreatic enzymes in the serum. There is evidence that acute intermittent porphyria and acute relapsing pancreatitis may have some etiological connection in this patient.

摘要

一名36岁女性因首次急性间歇性卟啉病发作入院。同时观察到血清淀粉酶和脂肪酶水平升高,以及淀粉酶清除率与肌酐清除率之比增加,从而诊断为急性胰腺炎。后者的病因无法确定。此外,观察到间接胆红素升高但无溶血证据,怀疑为吉尔伯特综合征。首次发作40周后,再次出现相同的腹痛发作,血清中胰腺酶升高。有证据表明,该患者的急性间歇性卟啉病和急性复发性胰腺炎可能存在某种病因学联系。

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引用本文的文献

1
A case of acute intermittent porphyria with acute pancreatitis.
Gastroenterol Jpn. 1991 Feb;26(1):90-4. doi: 10.1007/BF02779515.