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动物饲料中的治疗性抗生素与抗生素耐药性。

Therapeutic antibiotics in animal feeds and antibiotic resistance.

作者信息

Tollefson L, Altekruse S F, Potter M E

机构信息

Centre for Veterinary Medicine, United States Food and Drug Administration, Rockville, Maryland 20855, USA.

出版信息

Rev Sci Tech. 1997 Aug;16(2):709-15. doi: 10.20506/rst.16.2.1054.

Abstract

Recent statutory changes involving animal drugs are expected to facilitate the therapeutic use of antibiotics in animal feeds in the United States of America. The use of antibiotics in animal feeds is controversial due to the potential development of resistant bacterial pathogens in food-producing animals which are exposed to the antibiotics and the resultant public health risk. Zoonotic micro-organisms can be transmitted to humans through contact with animal populations, either directly or through the consumption of contaminated food. Recommendations to address the public health concerns include the strengthening of professional education in the areas of infectious diseases and the appropriate selection and use of antimicrobial agents, the development of a comprehensive food safety education programme for food-animal veterinarians and animal producers, and the development of surveillance programmes to monitor antimicrobial resistance among zoonotic pathogens. Early identification of emerging resistance can facilitate a timely and appropriate public health response.

摘要

近期涉及兽用药品的法规变化有望促进抗生素在美国动物饲料中的治疗性使用。由于接触抗生素的食用动物中可能会出现耐药性细菌病原体,并由此带来公共健康风险,因此在动物饲料中使用抗生素存在争议。人畜共患微生物可通过直接接触动物群体或食用受污染食物传播给人类。针对公共卫生问题的建议包括加强传染病领域的专业教育以及抗菌剂的合理选择和使用,为食用动物兽医和动物生产者制定全面的食品安全教育计划,以及制定监测计划以监测人畜共患病原体中的抗菌药物耐药性。尽早发现新出现的耐药性有助于及时做出适当的公共卫生应对措施。

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