其他抗肿瘤萜烯基醌类和萜烯基氢醌类。
Further antineoplastic terpenylquinones and terpenylhydroquinones.
作者信息
Miguel del Corral J M, Gordaliza M, Castro M A, Mahiques M M, San Feliciano A, García-Grávalos M D
机构信息
Departamento de Química Farmacéutica, Facultad de Farmacia, Universidad de Salamanca, Spain.
出版信息
Bioorg Med Chem. 1998 Jan;6(1):31-41. doi: 10.1016/s0968-0896(97)10007-4.
PMID:9502103
Abstract
Influences of the quinone/hydroquinone fragment and other structural features are considered in relation with the antineoplastic activity and selectivity of terpenylquinones/hydroquinones. Several compounds have shown IC50 values under the microM level.
摘要
考虑了醌/对苯二酚片段及其他结构特征对萜烯基醌/对苯二酚的抗肿瘤活性和选择性的影响。几种化合物的半数抑制浓度（IC50）值已显示在微摩尔水平以下。
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