Murphy K J, Brunberg J A, Quint D J, Kazanjian P H
Department of Radiology, University of Michigan Hospitals, Ann Arbor, USA.
AJNR Am J Neuroradiol. 1998 Feb;19(2):341-8.
Our purpose was to describe the MR findings and evolution of spinal cord abscess and to define those MR features that allow differentiation of cord infection from other intramedullary abnormalities.
We retrospectively reviewed the MR studies of all patients in whom intramedullary spinal cord abscess was proved either by blood or cerebrospinal fluid culture or by serologic examination at our institution between January 1988 and January 1996. The study group included four adults and two children, 7 to 74 years old (mean age, 38 years).
Initial MR studies showed intramedullary high signal on T2-weighted sequences with poorly defined marginal enhancement on T1-weighted images. On follow-up contrast-enhanced T1-weighted studies, the lesions had well-defined enhancing margins with central low signal intensity. After the initiation of therapy, T2 signal abnormalities decreased markedly and contrast-enhanced studies showed ring enhancement. These T1 findings resolved with treatment over serial studies in four patients. The organisms identified were Streptococcus milleria, S pyogenes, atypical mycobacteria, Mycobacterium tuberculosis, and Schistosoma mansoni (both children).
A characteristic sequence of imaging findings aids in the differentiation of cord infection from other intramedullary lesions.
我们的目的是描述脊髓脓肿的磁共振成像(MR)表现及演变过程,并确定那些能将脊髓感染与其他髓内异常区分开来的MR特征。
我们回顾性分析了1988年1月至1996年1月间在我院经血液或脑脊液培养或血清学检查证实为髓内脊髓脓肿的所有患者的MR研究。研究组包括4名成年人和2名儿童,年龄在7至74岁之间(平均年龄38岁)。
最初的MR研究显示,在T2加权序列上为髓内高信号,在T1加权图像上边缘强化不清晰。在后续的对比增强T1加权研究中,病变边缘强化清晰,中央信号强度低。开始治疗后,T2信号异常明显减轻,对比增强研究显示环状强化。在连续研究中,4例患者的这些T1表现经治疗后消失。鉴定出的病原体为米勒链球菌、化脓性链球菌、非典型分枝杆菌、结核分枝杆菌和曼氏血吸虫(两名儿童患者)。
一系列特征性的影像学表现有助于将脊髓感染与其他髓内病变区分开来。