Koberstein B, Wedell J, Balzer K
Medizinische Klinik I, Klinikums Kreis Herford.
Med Klin (Munich). 1998 Jan 15;93(1):43-6. doi: 10.1007/BF03045040.
The celiac sprue, a small intestinal disease usually becoming apparent by a malabsorption syndrome, is caused by gluten respectively gliadin intolerance which leads to intestinal mucosal damage finally resulting in complete villous atrophy.
A propos of the case of a 60-year old woman with an uneventful course of celiac sprue of many years we report about a rare complication of this disease. Investigating recurrent attacks of abdominal pain a barium contrast examination revealed an intestinal stenosis which clinically resulted in an acute abdomen finally requiring surgery. Histologically a chronic ulcerative jejunoileitis was found. The main differential diagnosis is a malignant intestinal lymphoma, this however couldn't be found. Regarding this differential diagnosis surgical removal of the diseased parts of the bowel is the therapy of choice. Because of the possible transition from ulcerative jejunoileitis to intestinal lymphoma a postoperative close follow-up is recommended.
乳糜泻是一种通常由吸收不良综合征表现出来的小肠疾病,由麸质或醇溶蛋白不耐受引起,导致肠黏膜损伤,最终造成完全性绒毛萎缩。
关于一名60岁女性多年来乳糜泻病情平稳的病例,我们报告了该疾病一种罕见的并发症。在调查反复出现的腹痛时,钡剂造影检查显示肠道狭窄,临床上导致急腹症,最终需要手术治疗。组织学检查发现为慢性溃疡性空肠回肠炎。主要鉴别诊断为肠道恶性淋巴瘤,但未发现此类病变。针对该鉴别诊断,手术切除病变肠段是首选治疗方法。鉴于溃疡性空肠回肠炎可能转变为肠道淋巴瘤,建议术后密切随访。