Beigi B, Westlake W, Mangelschots E, Chang B, Rich W, Riordan T
West Of England Eye Unit, Royal Devon and Exeter Hospital.
Br J Ophthalmol. 1997 Nov;81(11):953-5. doi: 10.1136/bjo.81.11.953.
The normal conjunctival flora is one of the main sources of intraocular contamination during cataract surgery. The theory that the positive anterior chamber (AC) pressure during phacoemulsification (phaco), and the smaller wound utilised, might reduce the rate of contamination was studied.
The peroperative AC aspirates of 210 consecutive patients undergoing cataract surgery were assessed. In group 1, 100 patients underwent a standard extracapsular cataract extraction (ECCE). In group 2, 110 patients underwent phacoemulsification of the crystal-line lens through a scleral tunnel. AC aspirates from the Simcoe irrigation/aspiration cannula (group 1) and phaco probe (group 2) were collected and microbiological studies performed after direct and enrichment cultures.
There were 29 (29%) positives in the ECCE group compared with 22 (20%) positive cultures from AC aspirates in the phaco group. Coagulase negative staphylococcus (CNS) was the commonest contaminant in both groups.
Although there was a higher rate of AC contamination during ECCE, the difference was not statistically significant (p > 0.10, chi 2 = 2.31).
正常结膜菌群是白内障手术期间眼内污染的主要来源之一。本研究探讨了超声乳化白内障吸除术（phaco）过程中前房（AC）正压以及较小的手术切口可能降低污染率的理论。
对连续210例接受白内障手术患者的术中前房吸出物进行评估。第1组100例患者接受标准囊外白内障摘除术（ECCE）。第2组110例患者通过巩膜隧道进行晶状体超声乳化术。收集来自Simcoe灌注/抽吸套管（第1组）和超声乳化探头（第2组）的前房吸出物，经直接培养和富集培养后进行微生物学研究。
ECCE组有29例（29%）阳性，相比之下，超声乳化组前房吸出物培养有22例（20%）阳性。凝固酶阴性葡萄球菌（CNS）是两组中最常见的污染物。
虽然ECCE期间前房污染率较高，但差异无统计学意义（p>0.10，χ²=2.31）。
