Tsui E Y, Gao X J, Zinman B
The Mount Sinai Hospital Samuel Lunenfeld Research Institute and The Department of Medicine, University of Toronto, Ontario, Canada.
Diabet Med. 1998 Feb;15(2):125-8. doi: 10.1002/(SICI)1096-9136(199802)15:2<125::AID-DIA532>3.0.CO;2-N.
The use of bioelectrical impedance analysis (BIA) for determining human body composition is widely accepted as a safe, rapid, and reliable technique. Although this technique has been validated in normal and obese individuals, only limited studies have been done in special populations. The use of BIA for the measurement of body composition in Type 2 (non-insulin dependent) diabetic patients would be of particular interest for both clinical and investigative studies. The aim of this study was to evaluate the validity of a new bipedal BIA device for the measurement of body composition in a population of individuals with Type 2 diabetes mellitus. The body composition of 48 male and 48 female Type 2 subjects was measured by BIA and dual energy X-ray absorptiometry (DXA). The percentage body fat determined by BIA was significantly correlated with % body fat determined by DXA (r = 0.89, p < 0.0001). Agreement analysis showed that BIA consistently overestimated % fat in female diabetic subjects by approximately 5% and underestimated % fat in male diabetic subjects by approximately 10% of the predicted value obtained with DXA. These differences were statistically significant but probably of minor clinical relevance. We conclude that BIA measurement by TBF 105 is a useful and reliable technique for measuring body composition in subjects with Type 2 diabetes mellitus.
生物电阻抗分析（BIA）用于测定人体成分，作为一种安全、快速且可靠的技术已被广泛接受。尽管该技术已在正常人和肥胖个体中得到验证，但针对特殊人群的研究却很有限。将BIA用于测量2型（非胰岛素依赖型）糖尿病患者的身体成分，对于临床和研究性研究都将具有特别的意义。本研究的目的是评估一种新型双足BIA设备在测量2型糖尿病患者群体身体成分方面的有效性。通过BIA和双能X线吸收法（DXA）测量了48名男性和48名女性2型受试者的身体成分。BIA测定的体脂百分比与DXA测定的体脂百分比显著相关（r = 0.89，p < 0.0001）。一致性分析表明，BIA持续高估女性糖尿病受试者的体脂百分比约5%，而低估男性糖尿病受试者的体脂百分比约为DXA预测值的10%。这些差异具有统计学意义，但可能在临床上的相关性较小。我们得出结论，通过TBF 105进行BIA测量是一种用于测量2型糖尿病患者身体成分的有用且可靠的技术。
