Chang F Y, Lu C L, Chen C Y, Lee S D, Tsai D S, Fu S E
Division of Gastroenterology, Taipei Veterans General Hospital, Taiwan, Republic of China.
Dig Dis Sci. 2001 Sep;46(9):1839-45. doi: 10.1023/a:1010614526685.
The present study aimed to validate the accuracy of a homemade applied potential tomography (APT) apparatus for liquid gastric emptying (GE). Twelve electrodes were placed in a circular array around the subjects. Ten electrodes in a rotated order recorded electrical current delivered from a driving pair of electrodes. Based on tomography, averaged signals of changed resistivity were constructed to display area changes. Six beakers were respectively placed into a saline-filled Perspex tank to measure their cross-sections. True beaker cross-sections are 2.01, 15.9, 18.8, 30.19, 38.48, and 63.61 cm2, respectively, whereas APT generated cross-sections were 7.9 +/- 2.9, 16.7 +/- 3.3, 22.4 +/- 4.9, 28 +/- 4.8, 48.7 +/- 7.6, 67 +/- 6.1 cm2, respectively (r = 0.98, P < 0.001). Twenty-four healthy males ingested 500-ml test solution to assess GE using both APT and scintigraphy. Only 20 (83.3%) subjects had a successful measurement. The APT half emptying time was 15.6 +/- 4.8 min, whereas scintigraphy was 21.9 +/- 6.3 min (r = 0.67, P < 0.01). In conclusion, our APT apparatus is a simple, noninvasive, and inexpensive way to assess liquid GE. Its clinical usefulness is confirmed using both phantom and human models.
本研究旨在验证一种自制的应用电位断层扫描（APT）设备用于液体胃排空（GE）的准确性。十二个电极围绕受试者呈圆形排列。十个电极按旋转顺序记录从一对驱动电极输送的电流。基于断层扫描，构建电阻率变化的平均信号以显示面积变化。六个烧杯分别放入一个装有盐水的有机玻璃水箱中以测量其横截面积。烧杯的真实横截面积分别为2.01、15.9、18.8、30.19、38.48和63.61平方厘米，而APT生成的横截面积分别为7.9±2.9、16.7±3.3、22.4±4.9、28±4.8、48.7±7.6、67±6.1平方厘米（r = 0.98，P < 0.001）。24名健康男性摄入500毫升测试溶液，使用APT和闪烁扫描法评估胃排空。只有20名（83.3%）受试者测量成功。APT的半排空时间为15.6±4.8分钟，而闪烁扫描法为21.9±6.3分钟（r = 0.67，P < 0.01）。总之，我们的APT设备是一种评估液体胃排空的简单、无创且廉价的方法。通过模型和人体模型均证实了其临床实用性。
