King H, Abdullaev B, Djumaeva S, Nikitin V, Ashworth L, Dobo M G
Division of Noncommunicable Diseases, World Health Organization, Geneva, Switzerland.
Diabet Med. 1998 Dec;15(12):1052-62. doi: 10.1002/(SICI)1096-9136(1998120)15:12<1052::AID-DIA661>3.0.CO;2-A.
Prevalence of glucose intolerance and other noncommunicable diseases has been examined in subjects aged 35 years and over in semirural and urban communities in the Fergana Valley in the eastern part of Uzbekistan, Central Asia. Diabetes and impaired glucose tolerance (IGT) were diagnosed according to the recommendations of the latest WHO Study Group on diabetes. Crude prevalence of diabetes was 9% and 5%, respectively, in semirural men and women, 13% and 9% in urban men and women. Crude prevalence of impaired glucose tolerance (IGT) was 6% and 9%, respectively, in semirural men and women, 9% and 8% in urban men and women. After adjustment for non-response, prevalence of diabetes was 5% and 4%, respectively, in semirural men and women and 8% in both urban men and women. Adjusted prevalence of IGT was 4% and 8%, respectively, in semirural men and women, 5% and 6% in urban men and women. The majority of subjects with a prior diagnosis of diabetes were being treated with oral hypoglycaemic agents. Almost one-half of subjects in both communities had body mass index of 25 kg m(-2) or greater. Central obesity (waist-hip ratio 0.95 or greater for men, 0.85 or greater for women) was observed in over one-quarter of subjects in both communities. Clinical hypertension was not frequent by international standards (9% in semirural subjects and 13% in urban subjects) but a number of subjects who were clinically normotensive claimed to be taking antihypertensive medication. It is concluded that glucose intolerance and central obesity are common in this region of Uzbekistan, about which there was previously little information.
在中亚乌兹别克斯坦东部费尔干纳谷地的半农村和城市社区，对35岁及以上人群的葡萄糖耐量异常及其他非传染性疾病的患病率进行了调查。根据世界卫生组织糖尿病最新研究小组的建议诊断糖尿病和糖耐量受损（IGT）。半农村男性和女性的糖尿病粗患病率分别为9%和5%，城市男性和女性分别为13%和9%。半农村男性和女性的糖耐量受损（IGT）粗患病率分别为6%和9%，城市男性和女性分别为9%和8%。在对无应答情况进行调整后，半农村男性和女性的糖尿病患病率分别为5%和4%，城市男性和女性均为8%。半农村男性和女性的IGT调整患病率分别为4%和8%，城市男性和女性分别为5%和6%。大多数先前被诊断为糖尿病的受试者正在接受口服降糖药治疗。两个社区中几乎一半的受试者体重指数达到或超过25kg/m²。两个社区中超过四分之一的受试者存在中心性肥胖（男性腰臀比0.95及以上，女性0.85及以上）。按照国际标准，临床高血压并不常见（半农村受试者中为9%，城市受试者中为13%），但一些临床血压正常的受试者声称正在服用抗高血压药物。得出的结论是，葡萄糖耐量异常和中心性肥胖在乌兹别克斯坦的这一地区很常见，而此前关于这方面的信息很少。
