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[长QT及孤立性U波交替一例的右心室单相动作电位记录]

[Recording of monophasic action potentials of the right ventricle in a case of long QT and isolated alternation of the U wave].

作者信息

Bonatti V, Finardi A, Botti G

出版信息

Arch Mal Coeur Vaiss. 1979 Nov;72(11):1180-6.

PMID:95088
Abstract

Monophasic action potentials (MAP) of the right ventricle were recorded with suction electrodes in a case of long QTU, electrical alternans of the U wave and "torsades de pointe" by hypocalcaemia. Two electrophysiological features were observed:--a notable difference in the duration of MAPs of different zones of the right ventricle;--a change in the length and appearances of phase 3 of the longest MAPs with an inconstant bulge (delayed repolarisation) in the terminal portion of these same MAPs. These changes, which favourise focal reentry phenomena and/or reciprocal conduction are the probable explanation of the pathogenesis of episodes of "torsades de pointe". A reduction in the conductance of potassium associated or related to hypocalcaemia probably explains the second of the two changes.

摘要

在一例QTU延长、U波电交替及低钙血症导致“尖端扭转型室速”的病例中,用吸引导电极记录右心室的单相动作电位(MAP)。观察到两个电生理特征:——右心室不同区域的MAP持续时间存在显著差异;——最长MAP的第3相长度和形态发生改变,且这些MAP的终末部分存在不恒定的隆凸(延迟复极)。这些有利于局灶性折返现象和/或折返传导的改变可能是“尖端扭转型室速”发作发病机制的解释。与低钙血症相关或有关的钾电导降低可能解释了这两种改变中的第二种。

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