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复方利多卡因乳膏在小儿包皮环切术阴茎背神经阻滞前的效果。

Efficacy of EMLA cream prior to dorsal penile nerve block for circumcision in children.

作者信息

Serour F, Mandelberg A, Zabeeda D, Mori J, Ezra S

机构信息

Division of Pediatric Surgery, Edith Wolfson Medical Center, Holon, Israel.

出版信息

Acta Anaesthesiol Scand. 1998 Feb;42(2):260-3. doi: 10.1111/j.1399-6576.1998.tb05119.x.

DOI:10.1111/j.1399-6576.1998.tb05119.x
PMID:9509213
Abstract

BACKGROUND

While circumcision may be performed solely with dorsal penile nerve block (DPNB), some painful steps in its use are skin needle penetration and infiltration of the anesthetic product. The objective of this study was to evaluate the efficacy of EMLA cream, prior to DPNB for circumcision in children.

METHODS

We conducted a prospective, randomized, double-blinded, placebo-controlled study with 42 children undergoing circumcision with DPNB alone, as an ambulatory procedure. Overall efficacy of EMLA cream (Group A) during needle penetration and infiltration was assessed using a visual analog scale, compared with a placebo cream (Group B). Patients were asked to orally report any pain during skin needle penetration and infiltration of anesthetic, and were graded from 1 to 4 according to intensity of pain, as 1) none, 2) slight, 3) moderate, or 4) severe. The child graded the global discomfort of the entire procedure using the visual analog scale.

RESULTS

When assessing needle penetration, none from Group A suffered any pain, whereas all from Group B suffered at least mild pain. Considering infiltration of the anesthetic, all children suffered at least slight-to-moderate pain. Based on the children's visual analog scale scores, EMLA cream has no beneficial effect for penile block.

CONCLUSION

Since the dorsal penile nerves are located under the Buck's fascia, topical anesthesia may not reach them and other techniques may be necessary to anesthetize them. We found that although EMLA cream is efficient as a topical anesthesia during needle penetration for DPNB, it has no beneficial effect during infiltration.

摘要

背景

虽然包皮环切术可仅采用阴茎背神经阻滞(DPNB)进行,但该操作中一些疼痛步骤包括皮肤针刺和麻醉剂注射。本研究的目的是评估在儿童包皮环切术使用DPNB之前涂抹复方利多卡因乳膏(EMLA)的效果。

方法

我们进行了一项前瞻性、随机、双盲、安慰剂对照研究,42名儿童仅接受DPNB包皮环切术,作为门诊手术。使用视觉模拟评分法评估复方利多卡因乳膏组(A组)在针刺和注射过程中的总体效果,并与安慰剂乳膏组(B组)进行比较。要求患者口头报告皮肤针刺和麻醉剂注射过程中的任何疼痛情况,并根据疼痛强度从1到4进行分级,即1)无疼痛,2)轻微疼痛,3)中度疼痛,或4)重度疼痛。儿童使用视觉模拟评分法对整个手术的总体不适程度进行评分。

结果

在评估针刺时,A组无人感到任何疼痛,而B组所有人至少感到轻微疼痛。考虑麻醉剂注射情况,所有儿童至少感到轻微至中度疼痛。根据儿童的视觉模拟评分法得分,复方利多卡因乳膏对阴茎阻滞无有益效果。

结论

由于阴茎背神经位于白膜下,局部麻醉可能无法作用于这些神经,可能需要其他技术来麻醉它们。我们发现,虽然复方利多卡因乳膏在DPNB针刺过程中作为局部麻醉有效,但在注射过程中并无有益效果。

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引用本文的文献

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World J Pediatr Surg. 2022 Nov 17;5(4):e000470. doi: 10.1136/wjps-2022-000470. eCollection 2022.
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A video study of pain relief during newborn male circumcision.一项关于新生儿男性包皮环切术中疼痛缓解的视频研究。
J Perinatol. 2006 Feb;26(2):106-10. doi: 10.1038/sj.jp.7211413.
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Pain management for neonatal circumcision.
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Paediatr Drugs. 2001;3(2):101-11. doi: 10.2165/00128072-200103020-00003.