Kodama K, Nakadaira H, Endoh K, Yamamoto M
Department of Hygiene and Preventive Medicine, Niigata University School of Medicine.
Jpn J Cancer Res. 1998 Jan;89(1):6-11. doi: 10.1111/j.1349-7006.1998.tb00471.x.
We calculated the standardized mortality ratios (SMRs) of biliary tract cancer (BTC) in Japan from 1981 to 1990 and statistically analyzed the results according to 333 Secondary Areas of Medical Care, as well as sex and subsite [gallbladder cancer (GBC) and extrahepatic bile duct cancer (BDC)], in order to examine geographic clustering patterns of BTC. In GBC in both sexes, the Secondary Areas of Medical Care with high SMRs were clustered in the eastern part of Japan. In BDC in both sexes, the Areas with high SMRs were clustered between the northern and eastern parts of Japan. In comparison with GBC, this clustering favored the northern part of Japan. In males, the clustering pattern in mortality from BTC was mainly due to the occurrence of BDC. In females, the clustering pattern in mortality from BTC reflected that of GBC. The clustering of BTC, especially GBC, seems to be related to the distribution of plains, basins, and rivers.
我们计算了1981年至1990年日本胆道癌(BTC)的标准化死亡率(SMR),并根据333个二级医疗区域以及性别和亚部位[胆囊癌(GBC)和肝外胆管癌(BDC)]对结果进行了统计分析,以研究BTC的地理聚集模式。在男女GBC中,SMR较高的二级医疗区域集中在日本东部。在男女BDC中,SMR较高的区域集中在日本北部和东部之间。与GBC相比,这种聚集更倾向于日本北部。在男性中,BTC死亡率的聚集模式主要归因于BDC的发生。在女性中,BTC死亡率的聚集模式反映了GBC的聚集模式。BTC的聚集,尤其是GBC,似乎与平原、盆地和河流的分布有关。