Nyström P O
Department of Surgery, University Hospital, Linköping, Sweden.
J Antimicrob Chemother. 1998 Jan;41 Suppl A:1-7. doi: 10.1093/jac/41.suppl_1.1.
Systemic inflammatory response syndrome (SIRS) is the clinical expression of the action of complex intrinsic mediators of the acute phase reaction. SIRS can be precipitated by events such as infection, trauma, pancreatitis, and surgery. At times, SIRS can compromise the function of various organ systems resulting in Multiple Organ Dysfunction Syndrome (MODS). SIRS and MODS are graded expressions of the inflammation associated with acute illness. Mild forms are frequent in general wards for both medical and surgical patients but those with severe forms require intensive care. Clinicians should learn to identify SIRS in their patients at an early stage to determine the underlying cause and treatment before the SIRS progresses to a more severe form.
全身炎症反应综合征（SIRS）是急性期反应复杂内在介质作用的临床表现。感染、创伤、胰腺炎和手术等事件可引发SIRS。有时，SIRS会损害各种器官系统的功能，导致多器官功能障碍综合征（MODS）。SIRS和MODS是与急性疾病相关炎症的分级表现。轻度形式在普通内科和外科病房的患者中很常见，但严重形式的患者需要重症监护。临床医生应学会在早期识别患者中的SIRS，以便在SIRS发展为更严重形式之前确定潜在病因并进行治疗。
