Schwartz G J, Haycock G B, Edelmann C M, Spitzer A
Pediatrics. 1976 Aug;58(2):259-63.
Based on statistical analysis of data in 186 children, a formula was derived which allows accurate estimation of glomerular filtration rate (GFR) from plasma creatinine and body lenght (GFR(ml/min/1.73 sq m) = 0.55 length (cm)/Per (mg/dl). Its application to clearance data in a separate group of 223 children reveals excellent agreement with GFR estimated by the Ccr (r = .935) or Cin (r = .905). This formula should be useful for adjusting dosages of drugs excreted by the kidney and detecting significant changes in renal function.
基于对186名儿童数据的统计分析，得出了一个公式，该公式可根据血浆肌酐和身长准确估算肾小球滤过率（GFR）（GFR（毫升/分钟/1.73平方米）= 0.55×身长（厘米）/血浆肌酐（毫克/分升））。将其应用于另一组223名儿童的清除率数据时，发现与通过肌酐清除率（Ccr）（r = 0.935）或菊粉清除率（Cin）（r = 0.905）估算的GFR具有极好的一致性。该公式对于调整经肾脏排泄药物的剂量以及检测肾功能的显著变化应是有用的。
