Shore D
Department of Molecular Biology, University of Geneva, Switzerland.
Curr Biol. 1998 Mar 12;8(6):R192-5. doi: 10.1016/s0960-9822(98)70122-8.
Recent results point to an important role for the nucleolus in the senescence of yeast cells. A further report suggests that the formation and preferential accumulation in mother cells of extrachromosomal rDNA circles is a cause of aging in yeast; this may be an ancient and conserved mechanism of senescence.
近期研究结果表明，核仁在酵母细胞衰老过程中发挥着重要作用。另一项报告指出，染色体外rDNA环在母细胞中的形成和优先积累是酵母衰老的一个原因；这可能是一种古老且保守的衰老机制。
