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[法国动物狂犬病的现状]

[Current status of animal rabies in France].

作者信息

Aubert M

机构信息

Laboratoire d'études sur la rage et la pathologie des animaux sauvages, Malzéville, France.

出版信息

Med Trop (Mars). 1997;57(3 Suppl):45-51.

PMID:9513178
Abstract

The main host reservoir and vector of rabies in Western Europe is the red fox (Vulpes vulpes). A vaccination strategy for this species has been developed and tested in Switzerland since 1978. Results indicate that the vaccine which is administered in spring and autumn for at least two consecutive years is more effective than destruction by shooting or gassing the animals. The same approach using bait containing increasingly effective and safe vaccines has been in use in France since 1986. By creating an immunological barrier from the English channel to the Swiss border, it has been possible to stop the southern progression of the disease. In the following years the vaccination program was extended to all contaminated areas in France (141,700 km2). From 1989 to 1996 rabies decreased in incidence by 99.7% and disappeared from 95% of the previously contaminated area. Although no case of rabies involving a non-flying mammal has been reported since October 1996, rabies cannot be considered as eradicated as long as places of active disease subsist in neighboring areas of Belgium and the Sarreland. Bat rabies in Europe is caused by two viral genotypes that have never been isolated in any species other than bats and man. A total of four cases of bat rabies have been diagnosed in France since 1989. All four cases occurred in the Serotine community including one in 1997. All cases of canine rabies reported in the last 20 years have been observed in imported animals. The last was in 1995 and could have been prevented by stricter border control.

摘要

西欧狂犬病的主要宿主和传播媒介是赤狐(狐属狐)。自1978年以来,瑞士已制定并测试了针对该物种的疫苗接种策略。结果表明,在春秋两季连续至少两年接种疫苗比射杀或毒气捕杀动物更有效。自1986年以来,法国一直在采用同样的方法,使用含有越来越有效和安全疫苗的诱饵。通过在英吉利海峡至瑞士边境建立免疫屏障,得以阻止该疾病向南蔓延。在接下来的几年里,疫苗接种计划扩展到了法国所有受污染地区(141,700平方公里)。从1989年到1996年,狂犬病发病率下降了99.7%,在之前95%的受污染地区消失。尽管自1996年10月以来没有报告过涉及非飞行哺乳动物的狂犬病病例,但只要比利时和萨尔兰州的邻近地区仍存在狂犬病活跃发病地点,就不能认为狂犬病已被根除。欧洲的蝙蝠狂犬病由两种病毒基因型引起,这两种基因型从未在蝙蝠和人类以外的任何物种中分离出来。自1989年以来,法国共诊断出4例蝙蝠狂犬病病例。所有4例病例都发生在伏翼群落,其中1例发生在1997年。过去20年报告的所有犬类狂犬病病例均在进口动物中观察到。最后一例发生在1995年,若加强边境管控本可预防。

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